The challenge of learning and teaching becomes evident when topics discussed are difficult to  appreciate and understand, e.g. at the molecular level; and the field of biology is replete with  these. Hence, a good target for interactive learning object (ILO) development is how the  immune system will respond to pathogenic activity. We demonstrated here the use of  simulation to learn and teach the basics of the human immune response to pathogenic activity  implemented as web-based ILO. Using SCORM [1], two ILO modules were developed, one each  for bacteria and virus, respectively. Assessment of the ILOs by randomly selected high school  and college students, and teachers, using the MERLOT [2-3] instrument to assess the accuracy of  informational content and effectiveness as a teaching tool. In a scale from 1 to 5, evaluation  results showed that the three groups of audience consistently rated the ILOs with mean ratings  of around 4.5 across three subject criteria of MERLOT, namely: Quality of Content, Ease of Use,  and Potential Effectiveness as a Learning Tool. This suggests that the ILOs rated well above  “very good” (i.e. 4), and which means that it met the standards in multimedia educational  resource for effective learning and teaching.

Journal of Multidisciplinary Research, Vol. 2, No. 1: 44-61.